We have multiple ongoing clinical trials. Sponsors for these include the StrokeNet program, the National Institutes of Health (NIH), as well as pharmaceutical trials. Many clinical trials can be categorized by the time point surrounding a stroke that is studied.

  1. Hyperacute: Stroke has occurred within the last six hours
  2. Acute: Stroke has occurred within the last 48 hours
  3. Subacute: Stroke has occurred from 48 hours up to about six months ago
  4. Chronic: Stroke has occurred in the last 6-12 months

About participating

What is a clinical trial? Clinical trials are organized experiments performed on human participants to determine the best way to treat, diagnose or prevent a disease. The information that scientists learn from clinical trials helps to improve the medical care for future patients. Clinical studies are carefully and ethically designed to protect participants from unnecessary side effects and other risks. Most clinical research is federally regulated with built-in safeguards to protect the participants.

Contact Jill Newgent at 314-747-5552 or 314-747-3795 if you have questions related to your ongoing participation in one of our clinical trials.

Active clinical trials

  • Conditions: Hypoxia-Ischemia, Brain Interventions: Device: taVNS Sponsors: Washington University School of Medicine Enrolling by invitation
  • Conditions: Ischemic Stroke Interventions: Biological: TS23 Sponsors: Translational Sciences, Inc.; University of Cincinnati; National Institute of Neurological Disorders and Stroke (NINDS); Medical University of South Carolina; University of Arizona Recruiting
  • Conditions: Stroke; Intracranial Atherosclerotic Stenosis (ICAS) Interventions: Other: MRI Sponsors: Yale University; National Institute of Neurological Disorders and Stroke (NINDS) Not yet recruiting
  • Conditions: Carotid Atherosclerosis; Asymptomatic Carotid Artery Stenosis; Carotid Artery Atheroma Interventions: Drug: 64Cu-25%-CANF-Comb; Drug: 64Cu-25%-CANF-Comb Sponsors: Washington University School of Medicine; Cedars-Sinai Medical Center; University of California, Santa Barbara; National Heart, Lung, and Blood Institute (NHLBI) Recruiting
  • Conditions: Prevention of Ischemic Stroke; Acute Non-cardioembolic Ischemic Stroke; High-risk Transient Ischemic Attack Interventions: Drug: Asundexian (BAY2433334); Drug: Placebo Sponsors: Bayer Recruiting
  • Conditions: Intra Cerebral Hemorrhage; ICH – Intracerebral Hemorrhage; ICH; Hemorrhage; Stroke; Clot (Blood); Brain; Clot Blood; Cognitive Decline; Cognitive Impairment; Survivorship; Memory Impairment; Motor Activity Sponsors: Johns Hopkins University; National Institute of Neurological Disorders and Stroke (NINDS) Enrolling by invitation
  • Conditions: Acute Ischemic Stroke Interventions: Device: transcutaneous auricular vagal nerve stimulation; Device: Sham transcutaneous vagal nerve stimulation Sponsors: Washington University School of Medicine Recruiting
  • Conditions: Intracranial Arteriosclerosis; Stroke Interventions: Drug: Ticagrelor + Aspirin; Drug: Rivaroxaban + Aspirin; Drug: Clopidogrel + Aspirin; Other: Risk Factor Management Sponsors: University of Florida; National Institute of Neurological Disorders and Stroke (NINDS); University of Cincinnati; Medical University of South Carolina; Janssen Scientific Affairs, LLC; AstraZeneca Recruiting
  • Conditions: Stroke; Thromboses, Intracranial; Aneurysm, Brain Interventions: Procedure: Stroke/Thrombectomy/Aneurysm-specific surgical procedures Sponsors: Medical University of South Carolina Recruiting
  • Conditions: Supratentorial Hemorrhage Interventions: Device: Aurora Surgiscope System Sponsors: Integra LifeSciences Corporation; Icahn School of Medicine at Mount Sinai; Oculus Imaging LLC Recruiting
  • Conditions: Subdural Hematoma Interventions: Procedure: Surgical Management; Device: Surgical Management + Treatment; Other: No Treatment; Device: Treatment Sponsors: Medtronic Neurovascular Clinical Affairs Recruiting
  • Conditions: Intracerebral Hemorrhage Interventions: Drug: Statins Sponsors: Beth Israel Deaconess Medical Center; NINDS Stroke Trials Network (StrokeNet); Canadian Stroke Consortium (CSC); University of Cincinnati; Medical University of South Carolina; Yale University; MetroHealth Medical Center; UH, Cleveland Medical Center; Spectrum Health Hospitals; West Virginia University; Columbia University; Weill Medical College of Cornell University; New York Presbyterian Brooklyn Methodist Hospital; Buffalo General Medical Center; State University of New York – Upstate Medical University; St. Joseph's Regional Medical Center, New Jersey; Tufts Medical Center; Massachusetts General Hospital; UMASS Memorial Medical Center; Brigham and Women's Hospital; Baystate Medical Center; University of Vermont Medical Center; […]
  • Conditions: Intracerebral Hemorrhage; Atrial Fibrillation Interventions: Drug: Apixaban; Drug: Aspirin Sponsors: Yale University; National Institute of Neurological Disorders and Stroke (NINDS) Recruiting
  • Conditions: Ischemic Stroke; Sleep Apnea; Sleep Apnea, Obstructive; TIA; Stroke; CPAP; Telemedicine; Home Sleep Apnea Test; Randomized Clinical Trial; Multicenter Trial Interventions: Device: CPAP Sponsors: University of Michigan; National Institute of Neurological Disorders and Stroke (NINDS); FusionHealth LLC; Medical University of South Carolina; University of Cincinnati Recruiting
  • Conditions: Acute Ischemic Stroke Interventions: Drug: Argatroban; Drug: Eptifibatide; Drug: Placebo Sponsors: Washington University School of Medicine; National Institute of Neurological Disorders and Stroke (NINDS) Active, not recruiting
  • Conditions: Cerebral Stroke Interventions: Device: EmboTrap® Revascularization Device; Device: CERENOVUS Large Bore Catheter/ EMBOVAC Aspiration Catheter Sponsors: Cerenovus, Part of DePuy Synthes Products, Inc. Recruiting
  • Conditions: Intracerebral Hemorrhage Interventions: Biological: Recombinant Activated Factor VII (rFVIIa); Biological: Placebo Sponsors: Joseph Broderick, MD; Novo Nordisk A/S; National Institute of Neurological Disorders and Stroke (NINDS) Recruiting
  • Conditions: Stroke Interventions: Drug: Apixaban; Drug: Aspirin Sponsors: Columbia University; National Institute of Neurological Disorders and Stroke (NINDS); University of Cincinnati; Medical University of South Carolina; Bristol-Myers Squibb; Pfizer; Roche Pharma AG; Weill Medical College of Cornell University; University of Washington Terminated