Research

As a world-renowned research institution, our section is committed to improving the quality of life of patients who have suffered a stroke through long-term patient care, ongoing basic research and clinical trials and continuing medical education. Multiple faculty members seek to understand the basics of stroke pathophysiology, genetics and treatment.

Additionally, we are involved in multiple ongoing clinical trials that seek to push the boundaries of medical and surgical management of stroke care.

Recent publications

• CSF-Based Volumetric Imaging Biomarkers Highlight Incidence and Risk Factors for Cerebral Edema After Ischemic Stroke
  February 1, 2024
  CSF-Based Volumetric Imaging Biomarkers Highlight Incidence and Risk Factors for Cerebral Edema After Ischemic StrokeBui, Q., Kumar, A., Chen, Y., Hamzehloo, A., Heitsch, L., Slowik, A., Strbian, D., Lee, J. M. & Dhar, R., Feb 2024, In: Neurocritical Care. 40, 1, p. 303-313 11 p.Research output: Contribution to journal › Article › peer-review
• Randomized Secondary Prevention Trials in Participants with Symptomatic Intracranial Atherosclerotic Stenosis
  February 1, 2024
  Randomized Secondary Prevention Trials in Participants with Symptomatic Intracranial Atherosclerotic StenosisDunn, L. E., Wang, Y., Kass-Hout, T. & Chiu, D., Feb 1 2024, In: Stroke. 55, 2, p. 324-334 11 p.Research output: Contribution to journal › Review article › peer-review
• Left atrial strain, embolic stroke of undetermined source, and atrial fibrillation detection
  January 1, 2024
  Left atrial strain, embolic stroke of undetermined source, and atrial fibrillation detectionBashir, Z., Chen, E. W., Wang, S., Shu, L., Goldstein, E. D., Rana, M., Kala, N., Dai, X., Mandel, D., Has, P., Xie, M., Wang, T., Dickey, J. B., Poppas, A., Simmons, J., Song, C., Yaghi, S. & Haines, P., Jan 2024, In: Echocardiography. 41, 1, e15738.Research output: Contribution to journal › Article › peer-review
• Comparison of cerebral oxygen extraction fraction using ASE and TRUST methods in patients with sickle cell disease and healthy controls
  January 1, 2024
  Comparison of cerebral oxygen extraction fraction using ASE and TRUST methods in patients with sickle cell disease and healthy controlsFellah, S., Ying, C., Wang, Y., Guilliams, K. P., Fields, M., Chen, Y., Lewis, J., Mirro, A., Cohen, R., Igwe, N., Eldeniz, C., Jiang, D., Lu, H., Powers, W. J., Lee, J-M., Ford, A. L. & An, H., 2024, (Accepted/In press) In: Journal of Cerebral Blood Flow and Metabolism.Research output: Contribution to journal › Article › peer-review
• History of obstructive sleep apnea associated with incident cognitive impairment in white but not black individuals in a US national cohort study
  December 1, 2023
  History of obstructive sleep apnea associated with incident cognitive impairment in white but not black individuals in a US national cohort studySawyer, R. P., Bennett, A., Blair, J., Molano, J., Timmerman, E., Foster, F., Karkoska, K., Hyacinth, H. I., Manly, J. J., Howard, V. J., Petrov, M. E., Hoffmann, C. M., Yu, F., Demel, S. L., Aziz, Y., Hooper, D., Hill, E. J., Johnson, J., Pounders, J. & Shatz, R., Dec 2023, In: Sleep Medicine. 112, p. 1-8 8 p.Research output: Contribution to journal › Article › peer-review
• White matter hyperintensity longitudinal morphometric analysis in association with Alzheimer disease
  October 1, 2023
  White matter hyperintensity longitudinal morphometric analysis in association with Alzheimer diseaseStrain, J. F., Phuah, C. L., Adeyemo, B., Cheng, K., Womack, K. B., McCarthy, J., Goyal, M., Chen, Y., Sotiras, A., An, H., Xiong, C., Scharf, A., Newsom-Stewart, C., Morris, J. C., Benzinger, T. L. S., Lee, J. M. & Ances, B. M., Oct 2023, In: Alzheimer's and Dementia. 19, 10, p. 4488-4497 10 p.Research output: Contribution to journal › Article › peer-review
• Toward Automated Detection of Silent Cerebral Infarcts in Children and Young Adults With Sickle Cell Anemia
  August 1, 2023
  Toward Automated Detection of Silent Cerebral Infarcts in Children and Young Adults With Sickle Cell AnemiaChen, Y., Wang, Y., Phuah, C. L., Fields, M. E., Guilliams, K. P., Fellah, S., Reis, M. N., Binkley, M. M., An, H., Lee, J. M., McKinstry, R. C., Jordan, L. C., Debaun, M. R. & Ford, A. L., Aug 1 2023, In: Stroke. 54, 8, p. 2096-2104 9 p.Research output: Contribution to journal › Article › peer-review
• Imaging biomarkers of cerebral edema automatically extracted from routine CT scans of large vessel occlusion strokes
  July 1, 2023
  Imaging biomarkers of cerebral edema automatically extracted from routine CT scans of large vessel occlusion strokesDhar, R., Kumar, A., Chen, Y., Begunova, Y., Olexa, M., Prasad, A., Carey, G., Gonzalez, I., Bhatia, K., Hamed, M., Heitsch, L., Mainali, S., Petersen, N. & Lee, J. M., Jul 1 2023, In: Journal of Neuroimaging. 33, 4, p. 606-616 11 p.Research output: Contribution to journal › Article › peer-review
• Liver pathology in retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations: vasculopathic disease beyond nodular regenerative hyperplasia
  May 1, 2023
  Liver pathology in retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations: vasculopathic disease beyond nodular regenerative hyperplasiaKhonde, P., Chatterjee, D., Bogacki, M., Liszewski, M. K., Ford, A. L., Miner, J., Atkinson, J. P. & Brunt, E. M., May 2023, In: Human Pathology. 135, p. 22-34 13 p.Research output: Contribution to journal › Article › peer-review
• Relationships of Hemoglobin Concentration, Ischemic Lesions, and Clinical Outcomes in Patients With Intracerebral Hemorrhage
  April 1, 2023
  Relationships of Hemoglobin Concentration, Ischemic Lesions, and Clinical Outcomes in Patients With Intracerebral HemorrhageRoh, D. J., Boehme, A., Mamoon, R., Hooper, D., Cottarelli, A., Ji, R., Mao, E., Kumar, A., Carvalho Poyraz, F., Demel, S. L., Spektor, V., Carmona, J., Hod, E. A., Ironside, N., Gutierrez, J., Guo, J., Konofagou, E., Elkind, M. S. V. & Woo, D., Apr 1 2023, In: Stroke. 54, 4, p. 1021-1029 9 p.Research output: Contribution to journal › Article › peer-review