Jin-Moo Lee

Jin-Moo Lee, MD, PhD

Andrew B. & Gretchen P. Jones Professor of Neurology
Chair, Department of Neurology
Co-Director, Stroke & Cerebrovascular Center
Co-Director, BJC Stroke Clinical Program
Section of Vascular Neurology, Department of Neurology
Barnes-Jewish Hospital and Washington University SOM

Jin-Moo Lee is the Andrew B. & Gretchen P. Jones Professor of Neurology and Chair for the Department of Neurology. He received his MD and PhD at Weill Cornell Medical College. After medical school he completed a Neurology residency at the University of Pennsylvania. He then came to Washington University where he completed a Vascular Neurology clinical fellowship followed by a post-doctoral research fellowship. He has served as a chair or board member on multiple national and international stroke associations.

Lee is active in both clinical work and research. His clinic focuses on patients with genetic causes of stroke. Similarly, his research interests center on the genetics of stroke. His lab focuses on targets in stroke that may mitigate brain injury and help with brain repair. 

A select list of Lee’s publications can be found below:

  1. Ibanez L, Heitsch L, Carrera C, Farias FHG, Dhar R, Budde J, Bergmann K, Bradley J, Harari O, Phuah CL, Lemmens R, Oliveira Souza AAV, Moniche F, Cabezas-Juan A, Arenillas JF, Krupinksi J, Cullell N, Torres-Aguila N, Muiño E, Cárcel-Márquez J, Marti-Fabregas J, Delgado-Mederos R, Marin-Bueno R, Hornick A, Vives-Bauza C, Navarro RD, Tur S, Jimenez C, Obach V, Segura T, Serrano-Heras G, Chung JW, Roquer J, Soriano-Tarraga C, Giralt-Steinhauer E, Mola-Caminal M, Pera J, Lapicka-Bodzioch K, Derbisz J, Davalos A, Lopez-Cancio E, Muñoz L, Tatlisumak T, Molina C, Ribo M, Bustamante A, Sobrino T, Castillo-Sanchez J, Campos F, Rodriguez-Castro E, Arias-Rivas S, Rodríguez-Yáñez M, Herbosa C, Ford AL, Arauz A, Lopes-Cendes I, Lowenkopf T, Barboza MA, Amini H, Stamova B, Ander BP, Sharp FR, Kim GM, Bang OY, Jimenez-Conde J, Slowik A, Stribian D, Tsai EA, Burkly LC, Montaner J, Fernandez-Cadenas I, Lee JM, Cruchaga C. Multi-ancestry genetic study in 5,876 patients identifies an association between excitotoxic genes and early outcomes after acute ischemic stroke.  medRxiv. 2020 Nov 3:2020.10.29.20222257. 
  2. Woo D, Anderson CD, Maguire J, Fornage M, Lee JM, Seshadri S, Markus HS, Majersik JJ, Jimenez-Conde J, Crawford K, Lindgren AG, Debette S.  Top research priorities for stroke genetics. Lancet Neurol. 2018 Aug;17(8):663-665. Epub 2018 Jul 17. 
  3. Fields ME, Mirro AE, Guilliams KP, Binkley MM, Gil Diaz L, Tan J, Fellah S, Eldeniz C, Chen Y, Ford AL, Shimony JS, King AA, An H, Smyser CD, Lee JM. Functional Connectivity Decreases with Metabolic Stress in Sickle Cell Disease.   Ann Neurol. 2020 Nov;88(5):995-1008. 
  4. Dhand A, Luke D, Lang C, Tsiaklides M, Feske S, Lee JM. Social networks and risk of delayed hospital arrival after acute stroke. Nat Commun. 2019 Mar 14;10(1):1206.
  5. Dhand A, Luke DA, Lang CE, Lee JM. Social Networks and Neurological Illness.  Nat Rev Neurol.  2016 Oct; 12(10):605-12
  6. KraftAW, BauerAQ, CulverJP, LeeJ-M. Sensory Deprivation Following Focal Ischemia Accelerates Remapping and Behavioral Recovery through Arc-Dependent Synaptic Plasticity.  Sci Transl Med, 2018, Jan 31;10(426).
  7. Kraft AW, Mitra A, Bauer AQ, Snyder AZ, Raichle ME, Culver JP, Lee JM. Visual experience sculpts whole-cortex spontaneous infraslow activity patterns through an Arc-dependent mechanism. Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):E9952-E9961.